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Sci. Aging Knowl. Environ., 17 August 2005
Vol. 2005, Issue 33, p. nf65
[DOI: 10.1126/sageke.2005.33.nf65]

NEWS FOCUS

Beta Testing

Lethargic pancreas gene might unleash diabetes

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2005/33/nf65

Abstract: If the manager at a fast-food joint always knocks off early, the other employees probably won't work very hard. Similarly, a "supervisor" gene that slacks off in pancreas cells might help trigger diabetes, a new study shows. Losing the gene thwarts the activity of other genes that control how the cells respond to glucose and release insulin. The work might provide a new target for antidiabetes drugs.

Citation: M. Leslie, Beta Testing. Sci. Aging Knowl. Environ. 2005 (33), nf65 (2005).

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