Sci. Aging Knowl. Environ., 24 August 2005
Vol. 2005, Issue 34, p. nf67
[DOI: 10.1126/sageke.2005.34.nf67]


Tuning Up the Pancreas

Mammalian version of yeast longevity protein boosts efficiency of insulin-making cells

Mitch Leslie

Abstract: Even the most adept mechanic can't make a Ford Focus run like a Porsche. But genetic tinkering can transform base-model mouse pancreas cells into high-performance insulin producers, according to new research. Cranking up a protein that promotes longevity in yeast and worms helps mice control their blood sugar, suggesting a new target for drugs to prevent and treat diabetes.

Citation: M. Leslie, Tuning Up the Pancreas. Sci. Aging Knowl. Environ. 2005 (34), nf67 (2005).

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