Sci. Aging Knowl. Environ., 2 February 2005
Vol. 2005, Issue 5, p. nf10
[DOI: 10.1126/sageke.2005.5.nf10]

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Plugged Up

Broken pump abets calcium overload after a stroke

R. John Davenport

http://sageke.sciencemag.org/cgi/content/full/2005/5/nf10

Abstract: Without a good bilge pump, ships can flood and sink--and so can cells. After a stroke, a cellular pump protein breaks down, allowing a deadly accumulation of calcium, new results reveal. The study uncovers a protein-eating molecule that dismantles the channel and suggests that preventing the razing might stave off stroke damage.

Citation: R. J. Davenport, Plugged Up. Sci. Aging Knowl. Environ. 2005 (5), nf10 (2005).

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