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Sci. Aging Knowl. Environ., 4 January 2006
Vol. 2006, Issue 1, p. nf1
[DOI: 10.1126/sageke.2006.1.nf1]


Uncoupling Insulin

SIRT1 boosts insulin release by blocking mitochondrial protein

Mitch Leslie

Abstract: Like a good actor, the Sir2 proteins don't stick to the same role. That's the message of a new study confirming that the proteins exert opposite effects on the glucose-regulating hormone insulin depending on whether they are in worms or mammals. The work fills in details of how the mammalian protein governs insulin.

Citation: M. Leslie, Uncoupling Insulin. Sci. Aging Knowl. Environ. 2006 (1), nf1 (2006).

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Science of Aging Knowledge Environment. ISSN 1539-6150