Sci. Aging Knowl. Environ., 8 February 2006
Vol. 2006, Issue 5, p. nf6
[DOI: 10.1126/sageke.2006.5.nf6]


Mucking With Metabolism

Inability to repair DNA damage in mitochondria could foster metabolic syndrome

Mary Beckman

Abstract: In some family businesses, one heir will strike out in a new direction, rejecting his or her expected fate. Similarly, a protein whose kin protect animals from cancer instead seems to guard mice against a metabolic disruption. The results show that flawed DNA repair could contribute to a condition called metabolic syndrome, and they support a link between the condition and mitochondria.

Citation: M. Beckman, Mucking With Metabolism. Sci. Aging Knowl. Environ. 2006 (5), nf6 (2006).

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