Sci. Aging Knowl. Environ., 3 May 2006
Vol. 2006, Issue 8, p. nf11
[DOI: 10.1126/sageke.2006.8.nf11]

NEWS FOCUS

In Praise of Insulin Resistance

Immune-cell metabolic defect might hinder atherosclerosis

Mitch Leslie

http://sageke.sciencemag.org/cgi/content/full/2006/8/nf11

Abstract: Insulin resistance, a condition in which body cells quit heeding the hormone, is a stop on the road to type 2 diabetes and a possible heart attack. But a new study of mice indicates that if particular immune cells become unresponsive to insulin, they help fend off one lethal complication of diabetes: atherosclerosis. The work suggests that insulin resistance in these cells curtails inflammation that promotes arterial obstructions.

Citation: M. Leslie, In Praise of Insulin Resistance. Sci. Aging Knowl. Environ. 2006 (8), nf11 (2006).

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