Sci. Aging Knowl. Environ., 3 May 2006
In Praise of Insulin Resistance
Immune-cell metabolic defect might hinder atherosclerosis
Abstract: Insulin resistance, a condition in which body cells quit heeding the hormone, is a stop on the road to type 2 diabetes and a possible heart attack. But a new study of mice indicates that if particular immune cells become unresponsive to insulin, they help fend off one lethal complication of diabetes: atherosclerosis. The work suggests that insulin resistance in these cells curtails inflammation that promotes arterial obstructions.
Citation: M. Leslie, In Praise of Insulin Resistance. Sci. Aging Knowl. Environ. 2006 (8), nf11 (2006).
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