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Sci. Aging Knowl. Environ., 3 October 2001
Vol. 2001, Issue 1, p. cp7

CLASSIC PAPERS

Selection for Delayed Senescence in Drosophila melanogaster

Leo S. Luckinbill, Robert Arking, Michael J. Clare, William C. Cirocco, and Steven A. Buck

http://sageke.sciencemag.org/cgi/content/abstract/sageke;2001/1/cp7

Abstract: Although theories of the evolution of senescence differ in the mode of action by which genes are thought to control the aging process, they all view the rate of senescence as an adaptable feature of life history and therefore modifiable by natural selection. Tests of theory, however, have generally yielded mixed results. The life-span of Drosophila melanogaster increased strongly in populations selected for late reproduction in these experiments. Delayed senescence was accompanied by a reduced early fecundity, suggesting pleiotropic genetic control of the aging process.

Reproduced by permission.

Leo S. Luckinbill, Robert Arking, Michael J. Clare, William C. Cirocco, Steven A. Buck, Selection for Delayed Senescence in Drosophila melanogaster. Evolution 38, 996-1003 (1984).

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Science of Aging Knowledge Environment. ISSN 1539-6150