Sci. Aging Knowl. Environ., 5 November 2003
JNK-ing Cellular Poisons
Embryo-shaping genetic pathway stanches oxidation
Key Words: real-time PCR serial analysis of gene expression hemipterous transcription factor
Abstract: Adults who are under pressure at work or harried by bill collectors don't usually need their childhood pacifiers or stuffed animals to cope. But organisms do seem to revisit their youth when they need to battle stress caused by metabolic byproducts, according to a new study. The work suggests that fruit flies reuse a molecular pathway that's crucial during embryonic development to orchestrate the adult's defenses against cell-wounding reactive oxygen species.
Citation: M. Leslie, JNK-ing Cellular Poisons. Sci. Aging Knowl. Environ. 2003 (44), nw149 (2003).
Science of Aging Knowledge Environment. ISSN 1539-6150