Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


SAGE KE Bulletin Board

Re: Record for oldest mouse

10 October 2001

Aubrey de Grey

I haven't heard of any Mus musculus exceeding 1407 days without either CR or a single-gene mutation. However, I've been involved recently in discussions aimed at setting up a prize for just such a record. The presently proposed prize structure, on which feedback would be most welcome, is described at http://www.gen.cam.ac.uk/MM.htm .

The main difference is that at present the plan does not bar the use of CR or single-gene mutations. This is partly for practical reasons (deciding whether a very mild reduction in caloric intake counts; the possibility of spontaneous - or simply undeclared! - loss-of-function mutations), and partly because further extending the lifespan of mice that have already been made very long-lived (e.g. by CR) may be more informative, at least in respect of relevance to long-lived species such as humans, than doing so to shorter-lived ones.


To Advertise     Find Products


Science of Aging Knowledge Environment. ISSN 1539-6150