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Historical (pre-1990) articles on aging.

Oxygen Poisoning and X-irradiation: A Mechanism in Common  Science 119, 623-626 (1954).
Rebeca Gerschman, Daniel L. Gilbert, Sylvanus W. Nye, Peter Dwyer, and Wallace O. Fenn
Science's SAGE KE (27 April 2005), http://sageke.sciencemag.org/cgi/content/abstract/2005/17/cp1
[Abstract] [PDF]

Aging: A Theory Based on Free Radical and Radiation Chemistry  J. Gerontol. 11, 298-300 (1956).
Denham Harman
Science's SAGE KE (18 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/37/cp14
[Abstract] [PDF]

Pleiotropy, Natural Selection, and the Evolution of Senescence  Evolution 11, 398-411 (1957).
George C. Williams
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp13
[Abstract] [PDF]

The Effects of Temperature and of Egg-Laying on the Longevity of Drosophila subobscura  J. Exp. Biol. 35, 832-842 (1958).
J. Maynard Smith
Science's SAGE KE (18 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/37/cp15
[Abstract] [PDF]

Review Lectures on Senescence: I. The Causes of Aging  Proc. R. Soc. London Ser. B 157, 115-127 (1962).
J. Maynard Smith
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp10
[Abstract] [PDF]

Biological Mechanisms Underlying the Aging Process: The Ideas and Techniques of Genetics Are Being Used to Obtain New Insight into the Problems of Aging  Science 141, 686-694 (1963).
Howard J. Curtis
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp1
[Abstract] [PDF]

The Maintenance of the Accuracy of Protein Synthesis and Its Relevance to Aging  Proc. Natl. Acad. Sci U.S.A. 49, 517-521 (1963).
L. E. Orgel
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp8
[Abstract] [PDF] [Correction (PDF)]

Detection of Inactive Enzyme Molecules in Ageing Organisms  Nature 227, 1214-1217 (1970).
Harriet Gershon and David Gershon
Science's SAGE KE (18 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/37/cp16
[Abstract] [PDF]

Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species  Proc. Natl. Acad. Sci. U.S.A. 71, 2169-2173 (1974).
R. W. Hart and R. B. Setlow
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp4
[Abstract] [PDF]

Mutation Selection and the Natural History of Cancer  Nature 255, 197-200 (1975).
John Cairns
Science's SAGE KE (28 June 2006), http://sageke.sciencemag.org/cgi/content/abstract/2006/10/cp1
[Abstract] [PDF]

Evolution of Human Longevity and the Genetic Complexity Governing Aging Rate  Proc. Natl. Acad. Sci. U.S.A. 72, 4664-4668 (1975).
Richard G. Cutler
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp2
[Abstract] [PDF]

DNA Repair and Longevity Assurance in Paramecium tetraurelia  Science 203, 1115-1117 (1979).
Joan Smith-Sonneborn
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp11
[Abstract] [PDF]

A Test of Evolutionary Theories of Senescence  Nature 287, 141-142 (1980).
Michael Rose and Brian Charlesworth
Science's SAGE KE (18 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/37/cp17
[Abstract] [PDF]

Life-Span Study of SPF Fischer 344 Male Rats Fed Ad Libitum or Restricted Diets: Longevity, Growth, Lean Body Mass and Disease  J. Gerontol. 37, 130-141 (1982).
Byung Pal Yu, Edward J. Masoro, Ikuo Murata, Helen A. Bertrand, and Frederick T. Lynd
Science's SAGE KE (18 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/37/cp18
[Abstract] [PDF]

Dietary Restriction in Mice Beginning at One Year of Age: Effect on Life-Span and Spontaneous Cancer Incidence  Science 215, 1415-1418 (1982).
Richard Weindruch and Roy L. Walford
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp12
[Abstract] [PDF]

Action of Food Restriction in Delaying the Aging Process  Proc. Natl. Acad. Sci. U.S.A. 79, 4239-4241 (1982).
E. J. Masoro, B. P. Yu, and H. A. Bertrand
Science's SAGE KE (8 January 2003), http://sageke.sciencemag.org/cgi/content/abstract/2003/1/cp1
[Abstract] [PDF]

Genetic Analysis of Life-Span in Caenorhabditis elegans  Proc. Natl. Acad. Sci. U.S.A. 79, 6603-6607 (1982).
Thomas E. Johnson and William B. Wood
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp6
[Abstract] [PDF]

Ovarian and Steroidal Influences on Neuroendocrine Aging Processes in Female Rodents  Endocr. Re. 5, 467-497 (1984).
Caleb E. Finch, Leda S. Felicio, Charles V. Mobbs, and James F. Nelson
Science's SAGE KE (18 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/37/cp19
[Abstract] [PDF]

Laboratory Evolution of Postponed Senescence in Drosophila melanogaster  Evolution 38, 1004-1010 (1984).
Michael R. Rose
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp9
[Abstract] [PDF]

Selection for Delayed Senescence in Drosophila melanogaster  Evolution 38, 996-1003 (1984).
Leo S. Luckinbill, Robert Arking, Michael J. Clare, William C. Cirocco, and Steven A. Buck
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp7
[Abstract] [PDF]

Effects of Food Restriction on Aging: Separation of Food Intake and Adiposity  Proc. Natl. Acad. Sci. U.S.A. 81, 1835-1838 (1984).
David E. Harrison, Jonathan Archer, and Clinton M. Astle
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp3
[Abstract] [PDF]

Effect of Dietary Restriction on Liver Protein Synthesis in Rats  J. Nutr. 115, 944-950 (1985).
Maria C. Birchenall-Sparks, Michael S. Roberts, Jeffrey Staeker, James E. Hardwick, and Arlan Richardson
Science's SAGE KE (18 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/37/cp20
[Abstract] [PDF]

The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis  Endocr. Rev. 7, 284-301 (1986).
Robert M. Sapolsky, Lewis C. Krey, and Bruce S. McEwen
Science's SAGE KE (25 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/38/cp21
[Abstract]

Aging Can Be Genetically Dissected Into Component Processes Using Long-Lived Lines of Caenorhabditis elegans  Proc. Natl. Acad. Sci. U.S.A. 84, 3777-3781 (1987).
Thomas E. Johnson
Science's SAGE KE (3 October 2001), http://sageke.sciencemag.org/cgi/content/abstract/2001/1/cp5
[Abstract] [PDF]

A Mutation in the age-1 Gene in Caenorhabditis elegans Lengthens Life and Reduces Hermaphrodite Fertility  Genetics 118, 75-86 (1988).
David B. Friedman and Thomas E. Johnson
Science's SAGE KE (25 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/38/cp22
[Abstract]

Three Mutants That Extend Both Mean and Maximum Life Span of the Nematode, Caenorhabditis elegans, Define the age-1 Gene  J. Gerontol. 43, B102-B109 (1988).
David B. Friedman and Thomas E. Johnson
Science's SAGE KE (25 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/38/cp23
[Abstract]

Murine Chromosomal Regions Correlated With Longevity  Genetics 118, 693-704 (1988).
Rebecca Gelman, Ada Watson, Roderick Bronson, and Edmond Yunis
Science's SAGE KE (25 September 2002), http://sageke.sciencemag.org/cgi/content/abstract/2002/38/cp24
[Abstract]


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Science of Aging Knowledge Environment. ISSN 1539-6150